The combined QB3/Chemistry Mass Spectrometry Facility at UC Berkeley features state-of-the-art mass spectrometers, that are capable of analyzing a wide variety of samples. The facility provides acquisition of mass spectra and accurate mass measurements of biological, organic and inorganic compounds, as well as mass measurements of intact proteins, lipids, oligosaccharides, and non-covalent protein-protein and protein-ligand complexes and supramolecular coordination clusters. The facility also provides advanced proteomics analysis. This involves protein identification using mass spectral data as well as identification of posttranslational modifications. In addition, the facility provides ion mobility spectrometry. The facility also operates an open access MALDI-TOF instrument available to trained users.
The QB3/Chemistry Mass Spectrometry Facility is available to all researchers on the UC Berkeley campus as well as other UC campuses. The facility can accept samples from outside the University in certain cases. However, the University of California is a nonprofit organization and as such does not compete with private industry. Before contacting us, researchers not affiliated with UC are encouraged to seek services from a commercial laboratory. For information regarding this policy or sample analysis, please contact Dr. Ulla Andersen (email: norklit AT berkeley DOT edu).
Sample Submission for the QB3/Chemistry Mass Spectrometry Facility during Phase 2 of campus COVID-19 reopening
A space has been created for sample drop-off in the Stanley Hall Loading Dock. The space is located on the outer part of the loading dock, by the big gas tank, and will be accessible Monday to Friday from 9:00 am to 3:00 pm.
Samples sealed in appropriate containers and taped to a completed submission form can be left in the blue basket labeled QB3/Chemistry Mass Spectrometry Facility (see photos below). Samples will be collected from the loading dock twice daily at 9:00 am and 3:00 pm. Researchers with access to Stanley Hall can place their samples in a box by B207 instead.
The submitters will receive an email when their spectra are ready for pick up.
An electronic copy can be emailed to the user upon request. If needed, the submission form can be found here. Any special details or instructions regarding sample analysis must be included on the form. A separate page can be used if necessary. It is highly recommended that researchers from the same group coordinate with each other to submit their samples in bulk, to help limit traffic on campus as much as possible. In order to comply with density regulations, submitters cannot be present during the analysis.
What we do
• Identify unknowns
• Accurate mass measurements
• Structural determination
• Quantitative analysis
• “Native” mass spectrometry of complexes
• Ion mobility studies
Small (and large) molecules
• Biological, organic, inorganic, organometallic
• Proteins, peptides, mixtures, lipids, oligonucleotides, metabolites, etc.